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Zovirax intensive uk ase treatment, and a phase III clinical trial The company is also conducting development to create drugs for patients that lack the MHC class II DRB1 gene Santos, Brazil – June 08, 2016 Novartis AG (NVS) is investing $500 million in the development of multiple sclerosis (MS) treatment that targets the MHC class II DRB1 gene, which is a risk factor for the disease. In addition, company is conducting research to create a novel drug address the complex treatment of this disease. In June, Novartis AG and Bristol-Myers Squibb's Biogen Idec announced that they had entered into a collaborative partnership to further the research of a MHC class II based therapy for MS. The goal of collaboration is to develop a MHC class I-targeted therapy that will be more selective in its ability to clear disease from patients. The partnership will generate $250 million in annual biopharmaceutical license royalties from the MHC class I-targeted drug. MHC class I molecules are essential to the proper functioning of immune system. MHC class I molecules are also involved in the formation of B-cell epithelium and thus can play a role in various inflammatory diseases and immune activation, including MS its relapsing form sclerosis. Patients with MS have reduced expression of the MHC class I molecule DRB1. Individuals have been unable to clear or many types of pathogens from the CNS by targeting protein on the surface of MHC class I molecules. As a consequence, the immune complexes and diseases that occur in patients with MS are more difficult to treat. In addition can u buy zovirax cream over the counter to a clinical development program advance the biotechnology, Novartis is developing a new drug candidate and proof-of-concept study that will validate the safety and efficacy of immunotherapy in multiple sclerosis patients. MHC class II genes are also involved in the immune system response to many viruses, and in a variety of bacterial infections. For many diseases, including the one Sildenafil online uk for which research being conducted is performed, targeting the MHC class II gene may provide a more selective method to fight viral infections. If proven safe in multiple sclerosis patients, the treatment could lead to significant clinical opportunities. "By using our expertise as a global manufacturer of immune-supportive products to help solve a disease that affects more than 5,000,000 people worldwide, we aim to make a real difference in the lives of people with MS," said Dr. Alexander Pfaffenroth, President and Chief Executive Officer of Novartis. "By leveraging our knowledge of multiple sclerosis, we have identified a new approach to addressing critical patient population for whom other medications may not be appropriate," said Dr. Mark E. Rosenbloom Director, Vaccine Development at Novartis. "MS is an extraordinarily complex disease and we believe by focusing on this patient population and by developing conducting our own research, a new therapeutic approach may be found. These results will crucial in the development of a new, MHC class II-specific vaccine." "I'm thrilled with the outcome of this collaboration with Novartis and Bristol-Myers"

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